Cargando…

Patient‐derived xenograft models of non‐small cell lung cancer for evaluating targeted drug sensitivity and resistance

Patient‐derived xenograft (PDX) models are a useful tool in cancer biology research. However, the number of lung cancer PDX is limited. In the present study, we successfully established 10 PDX, including three adenocarcinoma (AD), six squamous cell carcinoma (SQ) and one large cell carcinoma (LA), f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kita, Kenji, Fukuda, Koji, Takahashi, Hiro, Tanimoto, Azusa, Nishiyama, Akihiro, Arai, Sachiko, Takeuchi, Shinji, Yamashita, Kaname, Ohtsubo, Koshiro, Otani, Sakiko, Yanagimura, Naohiro, Suzuki, Chiaki, Ikeda, Hiroko, Tamura, Masaya, Matsumoto, Isao, Yano, Seiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778641/ https://www.ncbi.nlm.nih.gov/pubmed/31432603 http://dx.doi.org/10.1111/cas.14171

Ejemplares similares

Bronchoesophageal fistula formation after three courses of nivolumab for carcinoma of unknown primary with a subgroup of lung squamous cell carcinoma
por: Nishiyama, Akihiro, et al.
Publicado: (2020)

Reduced doses of dabrafenib and trametinib combination therapy for BRAF V600E-mutant non-small cell lung cancer prevent rhabdomyolysis and maintain tumor shrinkage: a case report
por: Adachi, Yuta, et al.
Publicado: (2020)

Mediastinal Malignant Melanoma Markedly Shrinking in Response to Nivolumab
por: Sakaguchi, Hiroyuki, et al.
Publicado: (2021)

Inhibition of EGFR and MEK surmounts entrectinib resistance in a brain metastasis model of NTRK1‐rearranged tumor cells
por: Suzuki, Chiaki, et al.
Publicado: (2022)

Multiple Malignant Lymphomas of the Bile Duct Developing after Spontaneous Regression of an Autoimmune Pancreatitis-like Mass
por: Ohtsubo, Koushiro, et al.
Publicado: (2020)

Trametinib overcomes KRAS‐G12V–induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR‐mutant lung cancer
por: Fukuda, Koji, et al.
Publicado: (2021)

STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosis
por: Yanagimura, Naohiro, et al.
Publicado: (2022)

Glycogen synthase kinase‐3 inhibition overcomes epithelial‐mesenchymal transition‐associated resistance to osimertinib in EGFR‐mutant lung cancer
por: Fukuda, Koji, et al.
Publicado: (2020)

In vitro and in vivo anti-tumor activity of alectinib in tumor cells with NCOA4-RET
por: Arai, Sachiko, et al.
Publicado: (2017)

Pulmonary carcinosarcoma showing an obvious response to pazopanib: a case report
por: Tanimoto, Azusa, et al.
Publicado: (2018)

MET amplification results in heterogeneous responses to osimertinib in EGFR‐mutant lung cancer treated with erlotinib
por: Nishiyama, Akihiro, et al.
Publicado: (2020)

Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer
por: Wang, Rong, et al.
Publicado: (2020)

In vivo imaging xenograft models for the evaluation of anti‐brain tumor efficacy of targeted drugs
por: Kita, Kenji, et al.
Publicado: (2017)

MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements
por: Takumi, Yohei, et al.
Publicado: (2022)

Severe Skin Toxicity Caused by Sequential Anti-PD-1 Antibody and Alectinib in Non-small-cell Lung Cancer: A Report of Two Cases and a Literature Review
por: Nishiyama, Akihiro, et al.
Publicado: (2021)

Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells
por: Tanimoto, Azusa, et al.
Publicado: (2014)

Phase I study of vorinostat with gefitinib in BIM deletion polymorphism/epidermal growth factor receptor mutation double‐positive lung cancer
por: Takeuchi, Shinji, et al.
Publicado: (2020)

Orthodontic Treatment for a Patient with Root Resorption of All Four Maxillary Incisors due to Bilaterally Impacted Canines
por: Yanoshita, Makoto, et al.
Publicado: (2022)

Amphiregulin triggered epidermal growth factor receptor activation confers in vivo crizotinib‐resistance of EML4‐ALK lung cancer and circumvention by epidermal growth factor receptor inhibitors
por: Taniguchi, Hirokazu, et al.
Publicado: (2016)

Impact of MET inhibition on small‐cell lung cancer cells showing aberrant activation of the hepatocyte growth factor/MET pathway
por: Taniguchi, Hirokazu, et al.
Publicado: (2017)

Androgen replacement therapy for cancer‐related symptoms in male: result of prospective randomized trial (ARTFORM study)
por: Izumi, Kouji, et al.
Publicado: (2021)

Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation
por: Takeuchi, Shinji, et al.
Publicado: (2017)

EGFR-TKI resistance promotes immune escape in lung cancer via increased PD-L1 expression
por: Peng, Shunli, et al.
Publicado: (2019)

Phase 1/2 study of alectinib in RET-rearranged previously-treated non-small cell lung cancer (ALL-RET)
por: Takeuchi, Shinji, et al.
Publicado: (2021)

Successful removal of an accidentally swallowed press‐through package sheet using a detachable snare: A case report
por: Mawatari, Fumihiro, et al.
Publicado: (2021)

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells
por: Nanjo, Shigeki, et al.
Publicado: (2015)

AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells
por: Taniguchi, Hirokazu, et al.
Publicado: (2019)

Xenografts derived from patients with head and neck cancer recapitulate patient tumour properties
por: Makita, Haruna, et al.
Publicado: (2021)

Diagnostic Accuracy of Commercially Available Automated External Defibrillators
por: Nishiyama, Takahiko, et al.
Publicado: (2015)

In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line
por: Nanjo, Shigeki, et al.
Publicado: (2015)

Erythropoietin Receptor Antagonist Suppressed Ectopic Hemoglobin Synthesis in Xenografts of HeLa Cells to Promote Their Destruction
por: Yasuda, Yoshiko, et al.
Publicado: (2015)

Inflammatory breast cancer: Vasculogenic mimicry and its hemodynamics of an inflammatory breast cancer xenograft model
por: Shirakawa, Kazuo, et al.
Publicado: (2003)

Accuracy of methionine-PET in predicting the efficacy of heavy-particle therapy on primary adenoid cystic carcinomas of the head and neck
por: Toubaru, Sachiko, et al.
Publicado: (2013)

Bevacizumab counteracts VEGF-dependent resistance to erlotinib in an EGFR-mutated NSCLC xenograft model
por: Masuda, Chinami, et al.
Publicado: (2017)

Efficacy and safety of amrubicin therapy after chemoimmunotherapy in small cell lung cancer patients
por: Kushiro, Kohei, et al.
Publicado: (2022)

Clinical Presentations of Teenage Outpatients Encountered by General Internists in Japanese Hospitals: A Cross-Sectional Study
por: Kita, Keiichiro, et al.
Publicado: (2023)

Deep-learning systems for diagnosing cleft palate on panoramic radiographs in patients with cleft alveolus
por: Kuwada, Chiaki, et al.
Publicado: (2022)

Reciprocal Association between the Apical Junctional Complex and AMPK: A Promising Therapeutic Target for Epithelial/Endothelial Barrier Function?
por: Tsukita, Kazuto, et al.
Publicado: (2019)

Development of human hepatocellular carcinoma in X-linked severe combined immunodeficient pigs: An orthotopic xenograft model
por: Mishima, Kohei, et al.
Publicado: (2021)

Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models
por: Okada, Seiji, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_sniue5h56v1flacv94snr53a3s