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Indoleamine 2,3‐dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma

Tryptophan metabolism is important to induce immune tolerance in tumors. To date, 3 types of tryptophan‐metabolizing enzymes have been identified: indoleamine 2,3‐dioxygenase 1 and 2 (IDO1 and IDO2) and tryptophan 2,3‐dioxygenase 2. Numerous studies have focused on IDO1 as its expression is enhanced...

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Detalles Bibliográficos
Autores principales:	Yamasuge, Wakana, Yamamoto, Yasuko, Fujigaki, Hidetsugu, Hoshi, Masato, Nakamoto, Kentaro, Kunisawa, Kazuo, Mouri, Akihiro, Nabeshima, Toshitaka, Saito, Kuniaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778659/ https://www.ncbi.nlm.nih.gov/pubmed/31444833 http://dx.doi.org/10.1111/cas.14179

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