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Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment

Pterygium is an old challenge for ophthalmic surgeons. Its final resolution is surgical intervention. New surgical techniques have been introduced to improve the outcome, however, the possibility of recurrence always exists. The purpose of this study was to evaluate the pterygium recurrence rate wit...

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Autores principales: Daponte, Pablo Luis, Cigna, Andrea, Lescano, Ovidio, Sipowicz, Federico, Peña, Brenda, Abud, Gabriel, Di-Virgilio, Gabriel, Chirinos, Adriana, Bodino, Gustavo Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Hypothesis, Discovery & Innovation Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778675/
https://www.ncbi.nlm.nih.gov/pubmed/31788488
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author Daponte, Pablo Luis
Cigna, Andrea
Lescano, Ovidio
Sipowicz, Federico
Peña, Brenda
Abud, Gabriel
Di-Virgilio, Gabriel
Chirinos, Adriana
Bodino, Gustavo Federico
author_facet Daponte, Pablo Luis
Cigna, Andrea
Lescano, Ovidio
Sipowicz, Federico
Peña, Brenda
Abud, Gabriel
Di-Virgilio, Gabriel
Chirinos, Adriana
Bodino, Gustavo Federico
author_sort Daponte, Pablo Luis
collection PubMed
description Pterygium is an old challenge for ophthalmic surgeons. Its final resolution is surgical intervention. New surgical techniques have been introduced to improve the outcome, however, the possibility of recurrence always exists. The purpose of this study was to evaluate the pterygium recurrence rate with a long-term follow-up, after surgery was performed with conjunctival autograft and fibrin glue as a biological adhesive. A retrospective case-series study was performed, reviewing cases operated from May 2008 to May 2018 with at least 1 year of follow-up in a private clinic in Buenos Aires, Argentina. The evaluation time-points were at 1 day, 20 days, 6 months, 1 year after surgery and then every year. All the procedures were performed by the same surgeon in single center. Topical Mitomycin C (MMC), 5-Fluorouracil (5-FU), cauterization and/or amniotic membrane were not used in any case. From a total of 159 operated eyes (82/77 women/men), pterygium was recurred in 7 eyes (4.4%); all of them detected at the second follow-up time-point (at day 20). Intraoperative complications did not occur, but at the postoperative stage, one case presented a conjunctival granuloma, which was surgically resolved. In conclusion, a low pterygium recurrence rate was observed after conjunctival autograft with fibrin glue. In our study, recurrence was found at the postoperative first month and did not recur until the end of follow-up for 10 years.
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spelling pubmed-67786752019-12-01 Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment Daponte, Pablo Luis Cigna, Andrea Lescano, Ovidio Sipowicz, Federico Peña, Brenda Abud, Gabriel Di-Virgilio, Gabriel Chirinos, Adriana Bodino, Gustavo Federico Med Hypothesis Discov Innov Ophthalmol Original Article Pterygium is an old challenge for ophthalmic surgeons. Its final resolution is surgical intervention. New surgical techniques have been introduced to improve the outcome, however, the possibility of recurrence always exists. The purpose of this study was to evaluate the pterygium recurrence rate with a long-term follow-up, after surgery was performed with conjunctival autograft and fibrin glue as a biological adhesive. A retrospective case-series study was performed, reviewing cases operated from May 2008 to May 2018 with at least 1 year of follow-up in a private clinic in Buenos Aires, Argentina. The evaluation time-points were at 1 day, 20 days, 6 months, 1 year after surgery and then every year. All the procedures were performed by the same surgeon in single center. Topical Mitomycin C (MMC), 5-Fluorouracil (5-FU), cauterization and/or amniotic membrane were not used in any case. From a total of 159 operated eyes (82/77 women/men), pterygium was recurred in 7 eyes (4.4%); all of them detected at the second follow-up time-point (at day 20). Intraoperative complications did not occur, but at the postoperative stage, one case presented a conjunctival granuloma, which was surgically resolved. In conclusion, a low pterygium recurrence rate was observed after conjunctival autograft with fibrin glue. In our study, recurrence was found at the postoperative first month and did not recur until the end of follow-up for 10 years. Medical Hypothesis, Discovery & Innovation Ophthalmology 2019 2019-10-01 /pmc/articles/PMC6778675/ /pubmed/31788488 Text en © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International License (http://creativecommons.org/licenses/by/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
spellingShingle Original Article
Daponte, Pablo Luis
Cigna, Andrea
Lescano, Ovidio
Sipowicz, Federico
Peña, Brenda
Abud, Gabriel
Di-Virgilio, Gabriel
Chirinos, Adriana
Bodino, Gustavo Federico
Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment
title Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment
title_full Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment
title_fullStr Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment
title_full_unstemmed Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment
title_short Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment
title_sort conjunctival autograft with fibrin glue for pterygium: a long term recurrence assessment
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778675/
https://www.ncbi.nlm.nih.gov/pubmed/31788488
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