Radiosynthesis and Preclinical Evaluation of (11)C-VA426, a Cyclooxygenase-2 Selective Ligand

Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expression may represent an important diagnostic tool. I...

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Detalles Bibliográficos
Autores principales: Carpinelli, Assunta, Rainone, Paolo, Belloli, Sara, Reale, Annalisa, Cappelli, Andrea, Germano, Giuliani, Murtaj, Valentina, Coliva, Angela, Di Grigoli, Giuseppe, Valeri, Angela, Gilardi, Maria Carla, Gianolli, Luigi, Anzini, Maurizio, Moresco, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778861/
https://www.ncbi.nlm.nih.gov/pubmed/31598112
http://dx.doi.org/10.1155/2019/5823261

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