Exploring the effects of extracranial injections of botulinum toxin type A on prolonged intracranial meningeal nociceptors responses to cortical spreading depression in female rats

BACKGROUND: Botulinum neurotoxin type A, an FDA-approved prophylactic drug for chronic migraine, is thought to achieve its therapeutic effect through blocking activation of unmyelinated meningeal nociceptors and their downstream communications with myelinated nociceptors and potentially the vasculat...

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Detalles Bibliográficos
Autores principales: Melo-Carrillo, Agustin, Strassman, Andrew M, Schain, Aaron J, Noseda, Rodrigo, Ashina, Sait, Adams, Aubrey, Brin, Mitchell F, Burstein, Rami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779016/
https://www.ncbi.nlm.nih.gov/pubmed/31475573
http://dx.doi.org/10.1177/0333102419873675

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