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Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix in vivo Can Induce Seizures in Neonatal Mice
It is well-known that hyaluronic acid (HA) as a component of brain extracellular matrix (ECM) plays a pivotal role in the nervous system and is involved in synaptic plasticity changes in vascular cognitive impairment and dementia. HA breakdown is a feature of the acute stage of stroke injury and may...
Autores principales: | Balashova, Alena, Pershin, Vladimir, Zaborskaya, Olga, Tkachenko, Natalia, Mironov, Andrey, Guryev, Evgeny, Kurbatov, Leonid, Gainullin, Murat, Mukhina, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779145/ https://www.ncbi.nlm.nih.gov/pubmed/31632233 http://dx.doi.org/10.3389/fnins.2019.01033 |
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