Natural Resistance of Leishmania infantum to Miltefosine Contributes to the Low Efficacy in the Treatment of Visceral Leishmaniasis in Brazil

In India, visceral leishmaniasis (VL) caused by Leishmania donovani has been successfully treated with miltefosine with a cure rate of > 90%. To assess the efficacy and safety of oral miltefosine against Brazilian VL, which is caused by Leishmania infantum, a phase II, open-label, dose-escalation...

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Detalles Bibliográficos
Autores principales: Carnielli, Juliana B. T., Monti-Rocha, Renata, Costa, Dorcas Lamounier, Molina Sesana, Aretha, Pansini, Laura N. N., Segatto, Marcela, Mottram, Jeremy C., Costa, Carlos Henrique Nery, Carvalho, Sílvio F. G., Dietze, Reynaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779219/
https://www.ncbi.nlm.nih.gov/pubmed/31436148
http://dx.doi.org/10.4269/ajtmh.18-0949

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