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Combining autophagy stimulators and cellulose ethers for therapy against prion disease

Prion diseases are fatal transmissible neurodegenerative disorders that affect animals and humans. Prions are proteinaceous infectious particles consisting of a misfolded isoform of the cellular prion protein PrP(C), termed PrP(Sc). PrP(Sc) accumulates in infected neurons due to partial resistance t...

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Detalles Bibliográficos
Autores principales: Abdulrahman, Basant A., Tahir, Waqas, Doh-Ura, Katsumi, Gilch, Sabine, Schatzl, Hermann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779372/
https://www.ncbi.nlm.nih.gov/pubmed/31578923
http://dx.doi.org/10.1080/19336896.2019.1670928