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A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective

Background  Stroke-associated pneumonia (SAP) is an important cause of poststroke morbidity and mortality. Several clinical risk scores predict the risk of SAP. In this study, we used the A (2) DS (2) score (age, atrial fibrillation, dysphagia, sex, and stroke severity) to assess the risk of SAP in...

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Autores principales: Vyas, Limesh, Kulshreshtha, Dinkar, Maurya, Pradeep, Singh, Ajai, Qavi, Abdul, Thacker, Anup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779542/
https://www.ncbi.nlm.nih.gov/pubmed/31595119
http://dx.doi.org/10.1055/s-0039-1697893
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author Vyas, Limesh
Kulshreshtha, Dinkar
Maurya, Pradeep
Singh, Ajai
Qavi, Abdul
Thacker, Anup
author_facet Vyas, Limesh
Kulshreshtha, Dinkar
Maurya, Pradeep
Singh, Ajai
Qavi, Abdul
Thacker, Anup
author_sort Vyas, Limesh
collection PubMed
description Background  Stroke-associated pneumonia (SAP) is an important cause of poststroke morbidity and mortality. Several clinical risk scores predict the risk of SAP. In this study, we used the A (2) DS (2) score (age, atrial fibrillation, dysphagia, sex, and stroke severity) to assess the risk of SAP in patients admitted with acute stroke. Methods  A high (5–10) and a low (0–4) A (2) DS (2) score was assigned to patients with acute stroke admitted to the neurology ward. Univariate binary logistic regression analysis was performed to find the strength of association of SAP and A (2) DS (2) score. Results  There were 250 patients with acute stroke of which 46 developed SAP. Forty-four patients developed SAP in high score as against 2 in low-score group (odds ratio [OR] = 0.03, 95% confidence interval [CI] = 0.01–0.15, p = 0.0001). A (2) DS (2) score >5 had sensitivity of 82.6% and specificity of 65.1% to predict SAP. The mean A (2) DS (2) score in patients with pneumonia was 7.02 ± 1.40 compared to 4.75 ± 1.92 in patients without pneumonia ( p = 0.0001). Conclusions  A (2) DS (2) score has a high sensitivity of 82% in predicting the risk of SAP and is a useful tool to monitor patients after acute stroke. A (2) DS (2) score can help in timely detection and prevention of SAP and reduction in caregiver’s burden.
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spelling pubmed-67795422019-10-08 A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective Vyas, Limesh Kulshreshtha, Dinkar Maurya, Pradeep Singh, Ajai Qavi, Abdul Thacker, Anup J Neurosci Rural Pract Background  Stroke-associated pneumonia (SAP) is an important cause of poststroke morbidity and mortality. Several clinical risk scores predict the risk of SAP. In this study, we used the A (2) DS (2) score (age, atrial fibrillation, dysphagia, sex, and stroke severity) to assess the risk of SAP in patients admitted with acute stroke. Methods  A high (5–10) and a low (0–4) A (2) DS (2) score was assigned to patients with acute stroke admitted to the neurology ward. Univariate binary logistic regression analysis was performed to find the strength of association of SAP and A (2) DS (2) score. Results  There were 250 patients with acute stroke of which 46 developed SAP. Forty-four patients developed SAP in high score as against 2 in low-score group (odds ratio [OR] = 0.03, 95% confidence interval [CI] = 0.01–0.15, p = 0.0001). A (2) DS (2) score >5 had sensitivity of 82.6% and specificity of 65.1% to predict SAP. The mean A (2) DS (2) score in patients with pneumonia was 7.02 ± 1.40 compared to 4.75 ± 1.92 in patients without pneumonia ( p = 0.0001). Conclusions  A (2) DS (2) score has a high sensitivity of 82% in predicting the risk of SAP and is a useful tool to monitor patients after acute stroke. A (2) DS (2) score can help in timely detection and prevention of SAP and reduction in caregiver’s burden. Thieme Medical and Scientific Publishers 2019-07 2019-09-16 /pmc/articles/PMC6779542/ /pubmed/31595119 http://dx.doi.org/10.1055/s-0039-1697893 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Vyas, Limesh
Kulshreshtha, Dinkar
Maurya, Pradeep
Singh, Ajai
Qavi, Abdul
Thacker, Anup
A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
title A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
title_full A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
title_fullStr A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
title_full_unstemmed A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
title_short A (2) DS (2) Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
title_sort a (2) ds (2) score to predict the risk of stroke-associated pneumonia in acute stroke: an indian perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779542/
https://www.ncbi.nlm.nih.gov/pubmed/31595119
http://dx.doi.org/10.1055/s-0039-1697893
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