Cargando…

A Novel Heterocyclic System Based on Natural Epoxyalantolactone

Natural sesquiterpene lactones which contain an exocyclic methylene group in the β-position of the lactone ring react readily with N-nucleophiles. When studying the reaction of the natural epoxyalantolactone with the primary amines we demonstrate the formation of a new heterocyclic system—the hydrog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klochkov, Sergey G., Pukhov, Sergey A., Afanasieva, Svetlana V., Neganova, Margarita E., Ananiev, Ivan V., Avila-Rodriguez, Marco, Tarasov, Vadim V., Aliev, Gjumrakch
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779722/ https://www.ncbi.nlm.nih.gov/pubmed/31632949 http://dx.doi.org/10.3389/fchem.2019.00655

Ejemplares similares

Unique indolizidine alkaloid securinine is a promising scaffold for the development of neuroprotective and antitumor drugs
por: Klochkov, Sergey, et al.
Publicado: (2021)

N-Alkylation of Anthracycline Antibiotics by Natural Sesquiterpene Lactones as a Way to Obtain Antitumor Agents with Reduced Side Effects
por: Neganova, Margarita, et al.
Publicado: (2021)

The Association of Sleep Disorders, Obesity and Sleep-Related Hypoxia with Cancer
por: Brzecka, Anna, et al.
Publicado: (2020)

Updated Understanding of the Degenerative Disc Diseases - Causes Versus Effects - Treatments, Studies and Hypothesis
por: Muresanu, Cristian, et al.
Publicado: (2020)

Application of Acyzol in the Context of Zinc Deficiency and Perspectives
por: Aliev, Gjumrakch, et al.
Publicado: (2019)

Malignant Transformation and Associated Biomarkers of Ovarian Endometriosis: A Narrative Review
por: Mikhaleva, Liudmila M., et al.
Publicado: (2020)

Current Understanding of Central Nervous System Drainage Systems: Implications in the Context of Neurodegenerative Diseases
por: Nikolenko, Vladimir N., et al.
Publicado: (2020)

Therapeutic Influence on Important Targets Associated with Chronic Inflammation and Oxidative Stress in Cancer Treatment
por: Neganova, Margarita, et al.
Publicado: (2021)

Aminoazole-Based Diversity-Oriented Synthesis of Heterocycles
por: Murlykina, Maryna V., et al.
Publicado: (2018)

Alzheimer’s Disease – Future Therapy Based on Dendrimers
por: Aliev, Gjumrakch, et al.
Publicado: (2019)

Increased Pain Sensitivity in Obese Patients After Lung Cancer Surgery
por: Majchrzak, Maciej, et al.
Publicado: (2019)

Novel Multitarget Hydroxamic Acids with a Natural Origin CAP Group against Alzheimer’s Disease: Synthesis, Docking and Biological Evaluation
por: Neganova, Margarita, et al.
Publicado: (2021)

Alterations of Astrocytes in the Context of Schizophrenic Dementia
por: Tarasov, Vadim V., et al.
Publicado: (2020)

Sleep Disorders Associated With Alzheimer's Disease: A Perspective
por: Brzecka, Anna, et al.
Publicado: (2018)

Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities
por: Rayavarapu, Srinuvasarao, et al.
Publicado: (2017)

Publisher Correction: Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities
por: Rayavarapu, Srinuvasarao, et al.
Publicado: (2020)

A Systematic In-silico Analysis of Helicobacter pylori Pathogenic Islands for Identification of Novel Drug Target Candidates
por: Nammi, Deepthi, et al.
Publicado: (2017)

π-Extension of heterocycles via a Pd-catalyzed heterocyclic aryne annulation: π-extended donors for TADF emitters
por: Spence, Katie A., et al.
Publicado: (2022)

2-Oxindole and related heterocycles: synthetic methodologies for their natural products and related derivatives
por: Sharma, Shivangi, et al.
Publicado: (2023)

The structural diversity of heterocycle-fused potassium cyclopentadienides
por: Nifant'ev, Ilya E., et al.
Publicado: (2019)

Applications of tert-butanesulfinamide in the synthesis of N-heterocycles via sulfinimines
por: Philip, Rose Mary, et al.
Publicado: (2020)

Green Protocols in Heterocycle Syntheses via 1,3-Dipolar Cycloadditions
por: Martina, Katia, et al.
Publicado: (2019)

Natural Compounds and Their Structural Analogs in Regio- and Stereoselective Synthesis of New Families of Water-Soluble 2H,3H-[1,3]thia- and -Selenazolo[3,2-a]pyridin-4-ium Heterocycles by Annulation Reactions
por: Potapov, Vladimir A., et al.
Publicado: (2020)

Heterocycles from cyclopropenones
por: Aly, Ashraf A., et al.
Publicado: (2022)

Synthesis of novel cyclopeptides containing heterocyclic skeletons
por: Hamdan, Fatima, et al.
Publicado: (2018)

Post-Ugi Cyclization for the Construction of Diverse Heterocyclic Compounds: Recent Updates
por: Bariwal, Jitender, et al.
Publicado: (2018)

N-Heterocyclic carbene iron complexes catalyze the ring-opening polymerization of lactide
por: Nylund, Pamela V. S., et al.
Publicado: (2022)

Manganese(iii) complexes stabilized with N-heterocyclic carbene ligands for alcohol oxidation catalysis
por: Rigoni, Giacomo, et al.
Publicado: (2023)

Assessment of Psychosocial Functioning of Mothers of Children with Diabetes Mellitus Compared to Mothers of Healthy Children
por: Makara-Studzińska, Marta, et al.
Publicado: (2019)

A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products
por: Palani, Vignesh, et al.
Publicado: (2020)

Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment
por: Bachurin, Sergey O., et al.
Publicado: (2017)

(Phosphanyl)phosphaketenes as building blocks for novel phosphorus heterocycles
por: Hansmann, Max M., et al.
Publicado: (2017)

Editorial: Green Synthesis of Heterocycles
por: Aricò, Fabio
Publicado: (2020)

Aromatic interactions with heterocycles in water
por: Tobajas-Curiel, Gloria, et al.
Publicado: (2023)

Medicinal Plants as a Potential and Successful Treatment Option in the Context of Atherosclerosis
por: Kirichenko, Tatiana V., et al.
Publicado: (2020)

A confinement of N-heterocyclic molecules in a metal–organic framework for enhancing significant proton conductivity
por: Nguyen, My V., et al.
Publicado: (2021)

Synergistic effect of natural chickpea leaf exudates acids in heterocyclization: a greener protocol for benzopyran synthesis
por: Mali, Snehali, et al.
Publicado: (2018)

(15)N labeling and analysis of (13)C–(15)N and (1)H–(15)N couplings in studies of the structures and chemical transformations of nitrogen heterocycles
por: Deev, Sergey L., et al.
Publicado: (2019)

Recent advances of N-heterocyclic carbenes in the applications of constructing carbo- and heterocyclic frameworks with potential biological activity
por: Li, Mei-Mei, et al.
Publicado: (2021)

Dialkyl Carbonates in the Green Synthesis of Heterocycles
por: Tundo, Pietro, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6dhbtrqrlejjuvm904j6l4h653