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Triggering Receptor Expressed on Myeloid Cells-1 Inhibitor Targeted to Endothelium Decreases Cell Activation

TREM-1 (Triggering Receptor Expressed on Myeloid cells-1) is an immunoreceptor expressed on neutrophils, monocytes/macrophages, and endothelial cells. It amplifies the inflammatory response driven by Toll-Like Receptors (TLR) engagement. The pharmacological inhibition of TREM-1 confers protection in...

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Detalles Bibliográficos
Autores principales:	Gibot, Sébastien, Jolly, Lucie, Lemarié, Jérémie, Carrasco, Kevin, Derive, Marc, Boufenzer, Amir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779727/ https://www.ncbi.nlm.nih.gov/pubmed/31632399 http://dx.doi.org/10.3389/fimmu.2019.02314

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