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Suppression of Glucagon-Like Peptide-1 Release by Inhibition of Intestinal NLRP3 Inflammasome Activation in Asc(–/–) and Nlrp3(–/–) Mice
The glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone secreted by intestinal enteroendocrine L-cells, which plays a crucial role in glucose control, regulation, and protection from different pathological conditions such as diabetes mellitus. The present study sought to test whether GLP-1...
Autores principales: | Chen, Yu, Kidd, Jason, Bhat, Owais M., Yuan, Xinxu, Hong, Jinni, He, Xingxiang, Li, Pin-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779826/ https://www.ncbi.nlm.nih.gov/pubmed/31632284 http://dx.doi.org/10.3389/fphys.2019.01213 |
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