Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans

CK2α is a constitutively active and highly conserved serine/threonine protein kinase that is involved in the regulation of key cellular metabolic pathways and associated with a variety of tumours and cancers. The most well-known CK2α inhibitor is the human clinical trial candidate CX-4945, which has...

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Detalles Bibliográficos
Autores principales: Ong, Belinda X., Yoo, Youngki, Han, Myeong Gil, Park, Jun Bae, Choi, Myung Kyung, Choi, Yeseul, Shin, Jeon-Soo, Bahn, Yong-Sun, Cho, Hyun-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779870/
https://www.ncbi.nlm.nih.gov/pubmed/31591414
http://dx.doi.org/10.1038/s41598-019-50678-z

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