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Neurotropic and modulatory effects of insulin-like growth factor II in Aplysia

Insulin-like growth factor II (IGF2) enhances memory in rodents via the mannose-6-phosphate receptor (M6PR), but the underlying mechanisms remain poorly understood. We found that human IGF2 produces an enhancement of both synaptic transmission and neurite outgrowth in the marine mollusk Aplysia cali...

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Detalles Bibliográficos
Autores principales:	Kukushkin, Nikolay Vadimovich, Williams, Sidney Paulina, Carew, Thomas James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779898/ https://www.ncbi.nlm.nih.gov/pubmed/31591438 http://dx.doi.org/10.1038/s41598-019-50923-5

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