Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism

Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC), that cause gastrointestinal infection leading to hemolytic uremic syndrome. The aim of this study was to investigate if Stx signals via ATP and if blockade of purinergic receptors could be protective. Stx in...

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Detalles Bibliográficos
Autores principales: Johansson, Karl E., Ståhl, Anne-Lie, Arvidsson, Ida, Loos, Sebastian, Tontanahal, Ashmita, Rebetz, Johan, Chromek, Milan, Kristoffersson, Ann-Charlotte, Johannes, Ludger, Karpman, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779916/
https://www.ncbi.nlm.nih.gov/pubmed/31591425
http://dx.doi.org/10.1038/s41598-019-50692-1

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