Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

BACKGROUND AND PURPOSE: Severe influenza A virus (IAV) infections are associated with damaging hyperinflammation that can be fatal. There is an urgent need to identify new therapeutic agents to treat severe and pathogenic IAV infections. Repurposing of drugs with an existing and studied pharmacokine...

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Detalles Bibliográficos
Autores principales: Rosli, Sarah, Kirby, Francis J., Lawlor, Kate E., Rainczuk, Kate, Drummond, Grant R., Mansell, Ashley, Tate, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780046/
https://www.ncbi.nlm.nih.gov/pubmed/31271646
http://dx.doi.org/10.1111/bph.14787

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