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The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging
Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780210/ https://www.ncbi.nlm.nih.gov/pubmed/31492008 http://dx.doi.org/10.3390/jcm8091392 |
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author | Pirani, Vittorio Pelliccioni, Paolo De Turris, Serena Rosati, Alessandro Franceschi, Alessandro Cesari, Claudia Nicolai, Michele Mariotti, Cesare |
author_facet | Pirani, Vittorio Pelliccioni, Paolo De Turris, Serena Rosati, Alessandro Franceschi, Alessandro Cesari, Claudia Nicolai, Michele Mariotti, Cesare |
author_sort | Pirani, Vittorio |
collection | PubMed |
description | Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluation and with the aid of a multimodal imaging examination. Methods: We hereby describe selected cases who came to our attention and were visited in our eye clinic. In all clinics, the use of retinal and optic disc multimodal imaging during ophthalmological evaluation allowed to make a diagnosis of an infectious disease. Results: In our tertiary referral center more than 60 patients with syphilis, tuberculosis and toxoplasmosis have been evaluated in the last two years: In 60% of cases the ophthalmological evaluation was secondary to a previous diagnosis of an infectious disease, while in the remaining cases the ophthalmologist, with the help of a multimodal imaging examination and clinical evaluation, represented the physician who leads to the diagnosis. Conclusion: Our results confirm how in these life-threatening pathologies a prompt diagnosis is mandatory and may benefit from a multidisciplinary and multimodal imaging approach, especially during ophthalmological evaluation. |
format | Online Article Text |
id | pubmed-6780210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67802102019-10-30 The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging Pirani, Vittorio Pelliccioni, Paolo De Turris, Serena Rosati, Alessandro Franceschi, Alessandro Cesari, Claudia Nicolai, Michele Mariotti, Cesare J Clin Med Article Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluation and with the aid of a multimodal imaging examination. Methods: We hereby describe selected cases who came to our attention and were visited in our eye clinic. In all clinics, the use of retinal and optic disc multimodal imaging during ophthalmological evaluation allowed to make a diagnosis of an infectious disease. Results: In our tertiary referral center more than 60 patients with syphilis, tuberculosis and toxoplasmosis have been evaluated in the last two years: In 60% of cases the ophthalmological evaluation was secondary to a previous diagnosis of an infectious disease, while in the remaining cases the ophthalmologist, with the help of a multimodal imaging examination and clinical evaluation, represented the physician who leads to the diagnosis. Conclusion: Our results confirm how in these life-threatening pathologies a prompt diagnosis is mandatory and may benefit from a multidisciplinary and multimodal imaging approach, especially during ophthalmological evaluation. MDPI 2019-09-05 /pmc/articles/PMC6780210/ /pubmed/31492008 http://dx.doi.org/10.3390/jcm8091392 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pirani, Vittorio Pelliccioni, Paolo De Turris, Serena Rosati, Alessandro Franceschi, Alessandro Cesari, Claudia Nicolai, Michele Mariotti, Cesare The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging |
title | The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging |
title_full | The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging |
title_fullStr | The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging |
title_full_unstemmed | The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging |
title_short | The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging |
title_sort | eye as a window to systemic infectious diseases: old enemies, new imaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780210/ https://www.ncbi.nlm.nih.gov/pubmed/31492008 http://dx.doi.org/10.3390/jcm8091392 |
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