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Indole-4-carboxaldehyde Isolated from Seaweed, Sargassum thunbergii, Attenuates Methylglyoxal-Induced Hepatic Inflammation

Glucose degradation is aberrantly increased in hyperglycemia, which causes various harmful effects on the liver. Glyoxalase-1 (Glo-1) is a ubiquitous cellular enzyme that participates in the detoxification of methylglyoxal (MGO), a cytotoxic byproduct of glycolysis that induces protein modification...

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Detalles Bibliográficos
Autores principales: Cha, Seon-Heui, Hwang, Yongha, Heo, Soo-Jin, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780312/
https://www.ncbi.nlm.nih.gov/pubmed/31438528
http://dx.doi.org/10.3390/md17090486