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Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality

Staphylococcal infections are extensively investigated in humans owing to the resistance of staphylococci to diverse antibiotics commonly used in hospitals. The resistance mechanism of methicillin-resistant Staphylococcus aureus has garnered the interest of researchers due to its risk to the global...

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Autores principales: Oh, Woo Taek, Jun, Jin Woo, Giri, Sib Sankar, Yun, Saekil, Kim, Hyoun Joong, Kim, Sang Guen, Kim, Sang Wha, Han, Se Jin, Kwon, Jun, Park, Se Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780347/
https://www.ncbi.nlm.nih.gov/pubmed/31500280
http://dx.doi.org/10.3390/microorganisms7090330
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author Oh, Woo Taek
Jun, Jin Woo
Giri, Sib Sankar
Yun, Saekil
Kim, Hyoun Joong
Kim, Sang Guen
Kim, Sang Wha
Han, Se Jin
Kwon, Jun
Park, Se Chang
author_facet Oh, Woo Taek
Jun, Jin Woo
Giri, Sib Sankar
Yun, Saekil
Kim, Hyoun Joong
Kim, Sang Guen
Kim, Sang Wha
Han, Se Jin
Kwon, Jun
Park, Se Chang
author_sort Oh, Woo Taek
collection PubMed
description Staphylococcal infections are extensively investigated in humans owing to the resistance of staphylococci to diverse antibiotics commonly used in hospitals. The resistance mechanism of methicillin-resistant Staphylococcus aureus has garnered the interest of researchers due to its risk to the global public health. Furthermore, the zoonotic potential of staphylococci has led to increased interest in their transmission mechanism via food, livestock, as well as domestic and wild animals. Although fish are globally consumed, there are only few studies on the potential threat of staphylococcal infection in aquatic animals. In this study, we present the first description of Staphylococcus xylosus infection and its pathogenicity in rainbow trout, which resulted in fish mortality and economic losses in trout fisheries. We focused on the pathogenic role of the bacterium and its influence on rainbow trout based on the clinical symptoms in the eyes. Staphylococcus xylosus infection induced exophthalmia and disrupted the primary immune barrier, which increased the possibility of other secondary bacterial infections in fish under poor conditions, resulting in continuous mortality.
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spelling pubmed-67803472019-10-30 Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality Oh, Woo Taek Jun, Jin Woo Giri, Sib Sankar Yun, Saekil Kim, Hyoun Joong Kim, Sang Guen Kim, Sang Wha Han, Se Jin Kwon, Jun Park, Se Chang Microorganisms Article Staphylococcal infections are extensively investigated in humans owing to the resistance of staphylococci to diverse antibiotics commonly used in hospitals. The resistance mechanism of methicillin-resistant Staphylococcus aureus has garnered the interest of researchers due to its risk to the global public health. Furthermore, the zoonotic potential of staphylococci has led to increased interest in their transmission mechanism via food, livestock, as well as domestic and wild animals. Although fish are globally consumed, there are only few studies on the potential threat of staphylococcal infection in aquatic animals. In this study, we present the first description of Staphylococcus xylosus infection and its pathogenicity in rainbow trout, which resulted in fish mortality and economic losses in trout fisheries. We focused on the pathogenic role of the bacterium and its influence on rainbow trout based on the clinical symptoms in the eyes. Staphylococcus xylosus infection induced exophthalmia and disrupted the primary immune barrier, which increased the possibility of other secondary bacterial infections in fish under poor conditions, resulting in continuous mortality. MDPI 2019-09-07 /pmc/articles/PMC6780347/ /pubmed/31500280 http://dx.doi.org/10.3390/microorganisms7090330 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oh, Woo Taek
Jun, Jin Woo
Giri, Sib Sankar
Yun, Saekil
Kim, Hyoun Joong
Kim, Sang Guen
Kim, Sang Wha
Han, Se Jin
Kwon, Jun
Park, Se Chang
Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality
title Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality
title_full Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality
title_fullStr Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality
title_full_unstemmed Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality
title_short Staphylococcus xylosus Infection in Rainbow Trout (Oncorhynchus mykiss) As a Primary Pathogenic Cause of Eye Protrusion and Mortality
title_sort staphylococcus xylosus infection in rainbow trout (oncorhynchus mykiss) as a primary pathogenic cause of eye protrusion and mortality
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780347/
https://www.ncbi.nlm.nih.gov/pubmed/31500280
http://dx.doi.org/10.3390/microorganisms7090330
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