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Poly(Cyclohexene Phthalate) Nanoparticles for Controlled Dasatinib Delivery in Breast Cancer Therapy
The effect on the activity in breast cancer models of the small tyrosine kinase inhibitor dasatinib (DAS), either alone or in combination with other antitumoral agents, has been recently explored. However, DAS is characterized by its low and highly pH-dependent solubility, which could lead to poor u...
Autores principales: | Niza, Enrique, Nieto-Jiménez, Cristina, Noblejas-López, María del Mar, Bravo, Iván, Castro-Osma, José Antonio, de la Cruz-Martínez, Felipe, Martínez de Sarasa Buchaca, Marc, Posadas, Inmaculada, Canales-Vázquez, Jesús, Lara-Sanchez, Agustín, Hermida-Merino, Daniel, Solano, Eduardo, Ocaña, Alberto, Alonso-Moreno, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780527/ https://www.ncbi.nlm.nih.gov/pubmed/31461998 http://dx.doi.org/10.3390/nano9091208 |
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