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Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a con...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780538/ https://www.ncbi.nlm.nih.gov/pubmed/31461971 http://dx.doi.org/10.3390/jcm8091317 |
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author | Opitz, Antje Hubert, Jan Beste, Christian Stock, Ann-Kathrin |
author_facet | Opitz, Antje Hubert, Jan Beste, Christian Stock, Ann-Kathrin |
author_sort | Opitz, Antje |
collection | PubMed |
description | Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a consequence of binge drinking, modulates the interplay between cognitive control and automaticity in a comparable way. Therefore, the purpose of this study was to investigate the effects of alcohol hangover on controlled versus automatic response selection and inhibition. N = 34 healthy young men completed a Simon Nogo task, once sober and once hungover. Hangover symptoms were experimentally induced by a standardized administration of alcoholic drinks (with high congener content) on the night before the hangover appointment. We found no significant hangover effects, which suggests that alcohol hangover did not produce the same functional deficits as an acute high-dose intoxication. Yet still, add-on Bayesian analyses revealed that hangover slightly impaired response selection, but not response inhibition. This pattern of effects cannot be explained with the current knowledge on how ethanol and its metabolite acetaldehyde may modulate response selection and inhibition via the dopaminergic or GABAergic system. |
format | Online Article Text |
id | pubmed-6780538 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67805382019-10-30 Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition Opitz, Antje Hubert, Jan Beste, Christian Stock, Ann-Kathrin J Clin Med Article Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a consequence of binge drinking, modulates the interplay between cognitive control and automaticity in a comparable way. Therefore, the purpose of this study was to investigate the effects of alcohol hangover on controlled versus automatic response selection and inhibition. N = 34 healthy young men completed a Simon Nogo task, once sober and once hungover. Hangover symptoms were experimentally induced by a standardized administration of alcoholic drinks (with high congener content) on the night before the hangover appointment. We found no significant hangover effects, which suggests that alcohol hangover did not produce the same functional deficits as an acute high-dose intoxication. Yet still, add-on Bayesian analyses revealed that hangover slightly impaired response selection, but not response inhibition. This pattern of effects cannot be explained with the current knowledge on how ethanol and its metabolite acetaldehyde may modulate response selection and inhibition via the dopaminergic or GABAergic system. MDPI 2019-08-27 /pmc/articles/PMC6780538/ /pubmed/31461971 http://dx.doi.org/10.3390/jcm8091317 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Opitz, Antje Hubert, Jan Beste, Christian Stock, Ann-Kathrin Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition |
title | Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition |
title_full | Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition |
title_fullStr | Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition |
title_full_unstemmed | Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition |
title_short | Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition |
title_sort | alcohol hangover slightly impairs response selection but not response inhibition |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780538/ https://www.ncbi.nlm.nih.gov/pubmed/31461971 http://dx.doi.org/10.3390/jcm8091317 |
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