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Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition

Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a con...

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Autores principales: Opitz, Antje, Hubert, Jan, Beste, Christian, Stock, Ann-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780538/
https://www.ncbi.nlm.nih.gov/pubmed/31461971
http://dx.doi.org/10.3390/jcm8091317
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author Opitz, Antje
Hubert, Jan
Beste, Christian
Stock, Ann-Kathrin
author_facet Opitz, Antje
Hubert, Jan
Beste, Christian
Stock, Ann-Kathrin
author_sort Opitz, Antje
collection PubMed
description Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a consequence of binge drinking, modulates the interplay between cognitive control and automaticity in a comparable way. Therefore, the purpose of this study was to investigate the effects of alcohol hangover on controlled versus automatic response selection and inhibition. N = 34 healthy young men completed a Simon Nogo task, once sober and once hungover. Hangover symptoms were experimentally induced by a standardized administration of alcoholic drinks (with high congener content) on the night before the hangover appointment. We found no significant hangover effects, which suggests that alcohol hangover did not produce the same functional deficits as an acute high-dose intoxication. Yet still, add-on Bayesian analyses revealed that hangover slightly impaired response selection, but not response inhibition. This pattern of effects cannot be explained with the current knowledge on how ethanol and its metabolite acetaldehyde may modulate response selection and inhibition via the dopaminergic or GABAergic system.
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spelling pubmed-67805382019-10-30 Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition Opitz, Antje Hubert, Jan Beste, Christian Stock, Ann-Kathrin J Clin Med Article Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a consequence of binge drinking, modulates the interplay between cognitive control and automaticity in a comparable way. Therefore, the purpose of this study was to investigate the effects of alcohol hangover on controlled versus automatic response selection and inhibition. N = 34 healthy young men completed a Simon Nogo task, once sober and once hungover. Hangover symptoms were experimentally induced by a standardized administration of alcoholic drinks (with high congener content) on the night before the hangover appointment. We found no significant hangover effects, which suggests that alcohol hangover did not produce the same functional deficits as an acute high-dose intoxication. Yet still, add-on Bayesian analyses revealed that hangover slightly impaired response selection, but not response inhibition. This pattern of effects cannot be explained with the current knowledge on how ethanol and its metabolite acetaldehyde may modulate response selection and inhibition via the dopaminergic or GABAergic system. MDPI 2019-08-27 /pmc/articles/PMC6780538/ /pubmed/31461971 http://dx.doi.org/10.3390/jcm8091317 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Opitz, Antje
Hubert, Jan
Beste, Christian
Stock, Ann-Kathrin
Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
title Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
title_full Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
title_fullStr Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
title_full_unstemmed Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
title_short Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition
title_sort alcohol hangover slightly impairs response selection but not response inhibition
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780538/
https://www.ncbi.nlm.nih.gov/pubmed/31461971
http://dx.doi.org/10.3390/jcm8091317
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