Bromophenolics from the Red Alga Polysiphonia decipiens

The isolation and the structure determination of a new bromophenolic compound, polysiphonol (10), as well as five previously reported compounds, (4–8), from the red alga Polysiphonia decipiens is reported. In addition, the absolute configuration of the natural product rhodomelol (8) could be unequiv...

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Autores principales: Lever, James, Curtis, Grace, Brkljača, Robert, Urban, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780756/
https://www.ncbi.nlm.nih.gov/pubmed/31454979
http://dx.doi.org/10.3390/md17090497
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author Lever, James
Curtis, Grace
Brkljača, Robert
Urban, Sylvia
author_facet Lever, James
Curtis, Grace
Brkljača, Robert
Urban, Sylvia
author_sort Lever, James
collection PubMed
description The isolation and the structure determination of a new bromophenolic compound, polysiphonol (10), as well as five previously reported compounds, (4–8), from the red alga Polysiphonia decipiens is reported. In addition, the absolute configuration of the natural product rhodomelol (8) could be unequivocally confirmed for the first time, and on biosynthetic grounds, the absolute configuration of polysiphonol (10) was tentatively suggested. Compounds 4–8 were evaluated for their antibacterial activity against both Gram-positive and Gram-negative bacteria, but none of the compounds showed any appreciable activity.
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spelling pubmed-67807562019-10-30 Bromophenolics from the Red Alga Polysiphonia decipiens Lever, James Curtis, Grace Brkljača, Robert Urban, Sylvia Mar Drugs Communication The isolation and the structure determination of a new bromophenolic compound, polysiphonol (10), as well as five previously reported compounds, (4–8), from the red alga Polysiphonia decipiens is reported. In addition, the absolute configuration of the natural product rhodomelol (8) could be unequivocally confirmed for the first time, and on biosynthetic grounds, the absolute configuration of polysiphonol (10) was tentatively suggested. Compounds 4–8 were evaluated for their antibacterial activity against both Gram-positive and Gram-negative bacteria, but none of the compounds showed any appreciable activity. MDPI 2019-08-26 /pmc/articles/PMC6780756/ /pubmed/31454979 http://dx.doi.org/10.3390/md17090497 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Lever, James
Curtis, Grace
Brkljača, Robert
Urban, Sylvia
Bromophenolics from the Red Alga Polysiphonia decipiens
title Bromophenolics from the Red Alga Polysiphonia decipiens
title_full Bromophenolics from the Red Alga Polysiphonia decipiens
title_fullStr Bromophenolics from the Red Alga Polysiphonia decipiens
title_full_unstemmed Bromophenolics from the Red Alga Polysiphonia decipiens
title_short Bromophenolics from the Red Alga Polysiphonia decipiens
title_sort bromophenolics from the red alga polysiphonia decipiens
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780756/
https://www.ncbi.nlm.nih.gov/pubmed/31454979
http://dx.doi.org/10.3390/md17090497
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