Nutritional Therapy Modulates Intestinal Microbiota and Reduces Serum Levels of Total and Free Indoxyl Sulfate and P-Cresyl Sulfate in Chronic Kidney Disease (Medika Study)

In chronic kidney disease (CKD), the gut-microbiota metabolites indoxyl sulfate (IS) and p-cresyl sulfate (PCS) progressively accumulate due to their high albumin-binding capacity, leading to clinical complications. In a prospective crossover controlled trial, 60 patients with CKD grades 3B–4 (GFR =...

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Detalles Bibliográficos
Autores principales: Di Iorio, Biagio Raffaele, Rocchetti, Maria Teresa, De Angelis, Maria, Cosola, Carmela, Marzocco, Stefania, Di Micco, Lucia, di Bari, Ighli, Accetturo, Matteo, Vacca, Mirco, Gobbetti, Marco, Di Iorio, Mattia, Bellasi, Antonio, Gesualdo, Loreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780815/
https://www.ncbi.nlm.nih.gov/pubmed/31510015
http://dx.doi.org/10.3390/jcm8091424

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