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Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study

The aim of this study was to determine the prevalence of early chronic kidney disease (EKD) (stages 1 and 2) and the factors associated. This was a populational study including individuals from 18–75 years randomly selected from 18 Primary Healthcare centers in the area of Barcelonès Nord and Maresm...

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Autores principales: Expósito, Carmen, Pera, Guillem, Rodríguez, Lluís, Arteaga, Ingrid, Martínez, Alba, Alumà, Alba, Doladé, María, Torán, Pere, Caballeria, Llorenç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780839/
https://www.ncbi.nlm.nih.gov/pubmed/31487800
http://dx.doi.org/10.3390/jcm8091384
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author Expósito, Carmen
Pera, Guillem
Rodríguez, Lluís
Arteaga, Ingrid
Martínez, Alba
Alumà, Alba
Doladé, María
Torán, Pere
Caballeria, Llorenç
author_facet Expósito, Carmen
Pera, Guillem
Rodríguez, Lluís
Arteaga, Ingrid
Martínez, Alba
Alumà, Alba
Doladé, María
Torán, Pere
Caballeria, Llorenç
author_sort Expósito, Carmen
collection PubMed
description The aim of this study was to determine the prevalence of early chronic kidney disease (EKD) (stages 1 and 2) and the factors associated. This was a populational study including individuals from 18–75 years randomly selected from 18 Primary Healthcare centers in the area of Barcelonès Nord and Maresme (Catalunya, Spain). Variables: anamnesis, physical examination, blood pressure, and analysis. EKD was defined with by a glomerular filtration rate (GFR) ≥60 mL/min/1.73 m(2) and albumin/creatinine ratio (ACR) ≥17 mg/g in men and ≥25 mg/g in women confirmed with two determinations. 2871 individuals: 43% men, mean age 55 years (19–75), 32.2% obese, 50.5% abdominal obesity, 21.1% hypertensive, and 10.6% diabetic. Prevalence of EKD: With one determination 157 individuals (5.5%), 110 men (9%) and 47 women (2.8%); with two determinations 109 individuals (3.8%), 85 men (7%), and 24 women (1.5%). Factors independently associated with the multivariate logistic regression model: Man (OR 3.35), blood pressure ≥ 135/85 mmHg (OR 2.29), BMI ≥ 30 kg/m(2) (OR 2.48), glycemia ≥ 100 mg/dL (OR 1.73), smoker (OR 1.67) and age (OR 1.04). The prevalence varies if the diagnosis is established based on one or two analytical determinations, overestimated if only one determination is made and depends on the value chosen to define urine albumin excretion.
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spelling pubmed-67808392019-10-30 Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study Expósito, Carmen Pera, Guillem Rodríguez, Lluís Arteaga, Ingrid Martínez, Alba Alumà, Alba Doladé, María Torán, Pere Caballeria, Llorenç J Clin Med Article The aim of this study was to determine the prevalence of early chronic kidney disease (EKD) (stages 1 and 2) and the factors associated. This was a populational study including individuals from 18–75 years randomly selected from 18 Primary Healthcare centers in the area of Barcelonès Nord and Maresme (Catalunya, Spain). Variables: anamnesis, physical examination, blood pressure, and analysis. EKD was defined with by a glomerular filtration rate (GFR) ≥60 mL/min/1.73 m(2) and albumin/creatinine ratio (ACR) ≥17 mg/g in men and ≥25 mg/g in women confirmed with two determinations. 2871 individuals: 43% men, mean age 55 years (19–75), 32.2% obese, 50.5% abdominal obesity, 21.1% hypertensive, and 10.6% diabetic. Prevalence of EKD: With one determination 157 individuals (5.5%), 110 men (9%) and 47 women (2.8%); with two determinations 109 individuals (3.8%), 85 men (7%), and 24 women (1.5%). Factors independently associated with the multivariate logistic regression model: Man (OR 3.35), blood pressure ≥ 135/85 mmHg (OR 2.29), BMI ≥ 30 kg/m(2) (OR 2.48), glycemia ≥ 100 mg/dL (OR 1.73), smoker (OR 1.67) and age (OR 1.04). The prevalence varies if the diagnosis is established based on one or two analytical determinations, overestimated if only one determination is made and depends on the value chosen to define urine albumin excretion. MDPI 2019-09-04 /pmc/articles/PMC6780839/ /pubmed/31487800 http://dx.doi.org/10.3390/jcm8091384 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Expósito, Carmen
Pera, Guillem
Rodríguez, Lluís
Arteaga, Ingrid
Martínez, Alba
Alumà, Alba
Doladé, María
Torán, Pere
Caballeria, Llorenç
Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study
title Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study
title_full Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study
title_fullStr Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study
title_full_unstemmed Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study
title_short Prevalence of Early Chronic Kidney Disease and Main Associated Factors in Spanish Population: Populational Study
title_sort prevalence of early chronic kidney disease and main associated factors in spanish population: populational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780839/
https://www.ncbi.nlm.nih.gov/pubmed/31487800
http://dx.doi.org/10.3390/jcm8091384
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