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Increased Ratio of Matrix Metalloproteinase-9 (MMP-9)/Tissue Inhibitor Metalloproteinase-1 from Alveolar Macrophages in Chronic Asthma with a Fast Decline in FEV(1) at 5-Year Follow-up
Chronic asthma is associated with progressive airway remodeling, which may contribute to declining lung function. An increase in matrix metalloproteinases-9 (MMP-9)/tissue inhibitor metalloproteinase-1 (TIMP-1) may indicate airway inflammation and bronchial injury. Bronchial biopsy specimens and alv...
Autores principales: | Chung, Fu-Tsai, Huang, Hung-Yu, Lo, Chun-Yu, Huang, Yu-Chen, Lin, Chang-Wei, He, Chih-Chen, He, Jung-Ru, Sheng, Te-Fang, Wang, Chun-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780991/ https://www.ncbi.nlm.nih.gov/pubmed/31547356 http://dx.doi.org/10.3390/jcm8091451 |
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