Antibody barriers to going viral

Antibody neutralization of a virus in vitro is often associated with protection against viral exposure in vivo, but the mechanisms operational in vivo are often unclear. By investigating a large number of antibodies, Earnest et al. (https://doi.org/10.1084/jem.20190736) show the importance of antibo...

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Detalles Bibliográficos
Autor principal: Burton, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781000/
https://www.ncbi.nlm.nih.gov/pubmed/31444247
http://dx.doi.org/10.1084/jem.20191099
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author Burton, Dennis R.
author_facet Burton, Dennis R.
author_sort Burton, Dennis R.
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description Antibody neutralization of a virus in vitro is often associated with protection against viral exposure in vivo, but the mechanisms operational in vivo are often unclear. By investigating a large number of antibodies, Earnest et al. (https://doi.org/10.1084/jem.20190736) show the importance of antibody effector function in neutralizing antibody protection against an emerging alphavirus in a mouse model.
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spelling pubmed-67810002020-04-07 Antibody barriers to going viral Burton, Dennis R. J Exp Med News Antibody neutralization of a virus in vitro is often associated with protection against viral exposure in vivo, but the mechanisms operational in vivo are often unclear. By investigating a large number of antibodies, Earnest et al. (https://doi.org/10.1084/jem.20190736) show the importance of antibody effector function in neutralizing antibody protection against an emerging alphavirus in a mouse model. Rockefeller University Press 2019-10-07 2019-08-23 /pmc/articles/PMC6781000/ /pubmed/31444247 http://dx.doi.org/10.1084/jem.20191099 Text en © 2019 Burton http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Burton, Dennis R.
Antibody barriers to going viral
title Antibody barriers to going viral
title_full Antibody barriers to going viral
title_fullStr Antibody barriers to going viral
title_full_unstemmed Antibody barriers to going viral
title_short Antibody barriers to going viral
title_sort antibody barriers to going viral
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781000/
https://www.ncbi.nlm.nih.gov/pubmed/31444247
http://dx.doi.org/10.1084/jem.20191099
work_keys_str_mv AT burtondennisr antibodybarrierstogoingviral

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