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ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands

Group 3 innate lymphoid cells (ILC3s) are the innate counterparts of Th17 that require the transcription factor RORγt for development and contribute to the defense against pathogens through IL-22 and IL-17 secretion. Proliferation and effector functions of Th17 require a specific mTOR-dependent meta...

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Detalles Bibliográficos
Autores principales: Di Luccia, Blanda, Gilfillan, Susan, Cella, Marina, Colonna, Marco, Huang, Stanley Ching-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781001/
https://www.ncbi.nlm.nih.gov/pubmed/31296736
http://dx.doi.org/10.1084/jem.20180549