Long-Term Physical (In)Stability of Spray-Dried Amorphous Drugs: Relationship with Glass-Forming Ability and Physicochemical Properties

This study shows the importance of the chosen method for assessing the glass-forming ability (GFA) and glass stability (GS) of a drug compound. Traditionally, GFA and GS are established using in situ melt-quenching in a differential scanning calorimeter. In this study, we included 26 structurally di...

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Detalles Bibliográficos
Autores principales: Edueng, Khadijah, Bergström, Christel A.S., Gråsjö, Johan, Mahlin, Denny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781026/
https://www.ncbi.nlm.nih.gov/pubmed/31438566
http://dx.doi.org/10.3390/pharmaceutics11090425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781026/
https://www.ncbi.nlm.nih.gov/pubmed/31438566
http://dx.doi.org/10.3390/pharmaceutics11090425

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