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Long-Term Physical (In)Stability of Spray-Dried Amorphous Drugs: Relationship with Glass-Forming Ability and Physicochemical Properties
This study shows the importance of the chosen method for assessing the glass-forming ability (GFA) and glass stability (GS) of a drug compound. Traditionally, GFA and GS are established using in situ melt-quenching in a differential scanning calorimeter. In this study, we included 26 structurally di...
Autores principales: | Edueng, Khadijah, Bergström, Christel A.S., Gråsjö, Johan, Mahlin, Denny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781026/ https://www.ncbi.nlm.nih.gov/pubmed/31438566 http://dx.doi.org/10.3390/pharmaceutics11090425 |
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