Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock

Extracellular vesicles (EVs) are mRNA-containing cell fragments shed into circulation during pathophysiological events. DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) regulate gene expression by modifying DNA methylation and altering transcription. Sepsis is a systemic insult resulting in vascul...

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Detalles Bibliográficos
Autores principales: Dakhlallah, Duaa A., Wisler, Jon, Gencheva, Marieta, Brown, Candice M., Leatherman, Erin R., Singh, Kanhaiya, Brundage, Kathy, Karsies, Todd, Dakhlallah, Ahmad, Witwer, Kenneth W., Sen, Chandan K., Eubank, Timothy D., Marsh, Clay B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781191/
https://www.ncbi.nlm.nih.gov/pubmed/31632618
http://dx.doi.org/10.1080/20013078.2019.1669881

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