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Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells

The application of chondrogenic gene sequences to human bone marrow-derived mesenchymal stromal cells (hMSCs) is an attractive strategy to activate the reparative activities of these cells as a means to enhance the processes of cartilage repair using indirect cell transplantation procedures that may...

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Detalles Bibliográficos
Autores principales: Morscheid, Stephanie, Venkatesan, Jagadeesh Kumar, Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781264/
https://www.ncbi.nlm.nih.gov/pubmed/31466339
http://dx.doi.org/10.3390/jcm8091326