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Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability

Over the past few decades, the amorphous solid dispersions (ASDs) technique has emerged as a promising strategy to enhance the in vitro/in vivo characteristic of hydrophobic drugs. The low aqueous solubility and poor bioavailability of atorvastatin calcium (ATO), a lipid-lowering drug, present chall...

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Detalles Bibliográficos
Autores principales:	Kwon, Jaewook, Giri, Bhupendra Raj, Song, Eon Soo, Bae, Jinju, Lee, Junseong, Kim, Dong Wuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781288/ https://www.ncbi.nlm.nih.gov/pubmed/31500147 http://dx.doi.org/10.3390/pharmaceutics11090461

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