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Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators

Loxoprofen (LOX) is a non-selective cyclooxygenase inhibitor that is widely used for the treatment of pain and inflammation caused by chronic and transitory conditions. Its alcoholic metabolites are formed by carbonyl reductase (CR) and they consist of trans-LOX, which is active, and cis-LOX, which...

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Detalles Bibliográficos
Autores principales:	Paudel, Sanjita, Shrestha, Aarajana, Cho, Piljoung, Shrestha, Riya, Kim, Younah, Lee, Taeho, Kim, Ju-Hyun, Jeong, Tae Cheon, Lee, Eung-Seok, Lee, Sangkyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781309/ https://www.ncbi.nlm.nih.gov/pubmed/31527544 http://dx.doi.org/10.3390/pharmaceutics11090479

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