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Intracellular Delivery of siRNAs Targeting AKT and ERBB2 Genes Enhances Chemosensitization of Breast Cancer Cells in a Culture and Animal Model
Pharmacotherapy as the mainstay in the management of breast cancer suffers from various drawbacks, including non-targeted biodistribution, narrow therapeutic and safety windows, and also resistance to treatment. Thus, alleviation of the constraints from the pharmacodynamic and pharmacokinetic profil...
Autores principales: | Fatemian, Tahereh, Moghimi, Hamid Reza, Chowdhury, Ezharul Hoque |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781320/ https://www.ncbi.nlm.nih.gov/pubmed/31484456 http://dx.doi.org/10.3390/pharmaceutics11090458 |
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