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Intracellular Delivery of siRNAs Targeting AKT and ERBB2 Genes Enhances Chemosensitization of Breast Cancer Cells in a Culture and Animal Model

Pharmacotherapy as the mainstay in the management of breast cancer suffers from various drawbacks, including non-targeted biodistribution, narrow therapeutic and safety windows, and also resistance to treatment. Thus, alleviation of the constraints from the pharmacodynamic and pharmacokinetic profil...

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Detalles Bibliográficos
Autores principales:	Fatemian, Tahereh, Moghimi, Hamid Reza, Chowdhury, Ezharul Hoque
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781320/ https://www.ncbi.nlm.nih.gov/pubmed/31484456 http://dx.doi.org/10.3390/pharmaceutics11090458

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