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Epigenetic synthetic lethality approaches in cancer therapy

The onset and development of malignant tumors are closely related to epigenetic modifications, and this has become a research hotspot. In recent years, a variety of epigenetic regulators have been discovered, and corresponding small molecule inhibitors have been developed, but their efficacy in soli...

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Detalles Bibliográficos
Autores principales: Yang, Haoshen, Cui, Wei, Wang, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781350/
https://www.ncbi.nlm.nih.gov/pubmed/31590683
http://dx.doi.org/10.1186/s13148-019-0734-x