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Early-life DNA methylation profiles are indicative of age-related transcriptome changes

BACKGROUND: Alterations to cellular and molecular programs with brain aging result in cognitive impairment and susceptibility to neurodegenerative disease. Changes in DNA methylation patterns, an epigenetic modification required for various CNS functions are observed with brain aging and can be prev...

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Detalles Bibliográficos
Autores principales:	Hadad, Niran, Masser, Dustin R., Blanco-Berdugo, Laura, Stanford, David R., Freeman, Willard M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781367/ https://www.ncbi.nlm.nih.gov/pubmed/31594536 http://dx.doi.org/10.1186/s13072-019-0306-5

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