Eph receptors and ephrins engage in cellular cannibalism

Eph receptors bind ephrins on neighboring cells, oligomerizing into adhesive complexes that recruit signaling molecules. Execution of their signature repulsive program then generates pulling forces, enabling a cell to engulf a piece of another cell. New mechanistic insights by Gong et al. (2019. J....

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Detalles Bibliográficos
Autor principal: Pasquale, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781436/
https://www.ncbi.nlm.nih.gov/pubmed/31537710
http://dx.doi.org/10.1083/jcb.201908074
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author Pasquale, Elena B.
author_facet Pasquale, Elena B.
author_sort Pasquale, Elena B.
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description Eph receptors bind ephrins on neighboring cells, oligomerizing into adhesive complexes that recruit signaling molecules. Execution of their signature repulsive program then generates pulling forces, enabling a cell to engulf a piece of another cell. New mechanistic insights by Gong et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201901032) define this process as a form of “cellular cannibalism.”
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spelling pubmed-67814362020-04-07 Eph receptors and ephrins engage in cellular cannibalism Pasquale, Elena B. J Cell Biol Commentaries Eph receptors bind ephrins on neighboring cells, oligomerizing into adhesive complexes that recruit signaling molecules. Execution of their signature repulsive program then generates pulling forces, enabling a cell to engulf a piece of another cell. New mechanistic insights by Gong et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201901032) define this process as a form of “cellular cannibalism.” Rockefeller University Press 2019-10-07 2019-09-19 /pmc/articles/PMC6781436/ /pubmed/31537710 http://dx.doi.org/10.1083/jcb.201908074 Text en © 2019 Pasquale http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Pasquale, Elena B.
Eph receptors and ephrins engage in cellular cannibalism
title Eph receptors and ephrins engage in cellular cannibalism
title_full Eph receptors and ephrins engage in cellular cannibalism
title_fullStr Eph receptors and ephrins engage in cellular cannibalism
title_full_unstemmed Eph receptors and ephrins engage in cellular cannibalism
title_short Eph receptors and ephrins engage in cellular cannibalism
title_sort eph receptors and ephrins engage in cellular cannibalism
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781436/
https://www.ncbi.nlm.nih.gov/pubmed/31537710
http://dx.doi.org/10.1083/jcb.201908074
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