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MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane
Metastasis is a major cause of cancer-related death. Membrane type 1–matrix metalloproteinase (MT1-MMP) is a critical protease for local invasion and metastasis. MT1-MMP is synthesized in the endoplasmic reticulum (ER) and transported in vesicles to invadopodia, specialized subdomains of the plasma...
Autores principales: | Miyagawa, Takuya, Hasegawa, Kana, Aoki, Yoko, Watanabe, Takuya, Otagiri, Yuka, Arasaki, Kohei, Wakana, Yuichi, Asano, Kenichi, Tanaka, Masato, Yamaguchi, Hideki, Tagaya, Mitsuo, Inoue, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781441/ https://www.ncbi.nlm.nih.gov/pubmed/31519727 http://dx.doi.org/10.1083/jcb.201808149 |
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