Cargando…
VPS37A directs ESCRT recruitment for phagophore closure
The process of phagophore closure requires the endosomal sorting complex required for transport III (ESCRT-III) subunit CHMP2A and the AAA ATPase VPS4, but their regulatory mechanisms remain unknown. Here, we establish a FACS-based HaloTag-LC3 autophagosome completion assay to screen a genome-wide C...
Autores principales: | Takahashi, Yoshinori, Liang, Xinwen, Hattori, Tatsuya, Tang, Zhenyuan, He, Haiyan, Chen, Han, Liu, Xiaoming, Abraham, Thomas, Imamura-Kawasawa, Yuka, Buchkovich, Nicholas J., Young, Megan M., Wang, Hong-Gang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781443/ https://www.ncbi.nlm.nih.gov/pubmed/31519728 http://dx.doi.org/10.1083/jcb.201902170 |
Ejemplares similares
-
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
por: Takahashi, Yoshinori, et al.
Publicado: (2018) -
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion
por: Tang, Zhenyuan, et al.
Publicado: (2019) -
ESCRT-mediated phagophore sealing during mitophagy
por: Zhen, Yan, et al.
Publicado: (2019) -
Vps27 recruits ESCRT machinery to endosomes during MVB sorting
por: Katzmann, David J., et al.
Publicado: (2003) -
Assembly of the AAA ATPase Vps4 on ESCRT-III
por: Shestakova, Anna, et al.
Publicado: (2010)