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Protein quality control in the secretory pathway

Protein folding is inherently error prone, especially in the endoplasmic reticulum (ER). Even with an elaborate network of molecular chaperones and protein folding facilitators, misfolding can occur quite frequently. To maintain protein homeostasis, eukaryotes have evolved a series of protein qualit...

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Detalles Bibliográficos
Autores principales: Sun, Zhihao, Brodsky, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781448/
https://www.ncbi.nlm.nih.gov/pubmed/31537714
http://dx.doi.org/10.1083/jcb.201906047

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