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Protein quality control in the secretory pathway
Protein folding is inherently error prone, especially in the endoplasmic reticulum (ER). Even with an elaborate network of molecular chaperones and protein folding facilitators, misfolding can occur quite frequently. To maintain protein homeostasis, eukaryotes have evolved a series of protein qualit...
Autores principales: | Sun, Zhihao, Brodsky, Jeffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781448/ https://www.ncbi.nlm.nih.gov/pubmed/31537714 http://dx.doi.org/10.1083/jcb.201906047 |
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