Cargando…

Comprehensive analysis of genomic alterations detected by next-generation sequencing-based tissue and circulating tumor DNA assays in Chinese patients with non-small cell lung cancer

While tumor genotyping is the standard treatment for patients with non-small cell lung cancer (NSCLC), spatial and temporal tumor heterogeneity and insufficient specimens can lead to limitations in the use of tissue-based sequencing. Circulating tumor DNA (ctDNA) fully encompasses tumor-specific seq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hua, Zhang, Junjie, Zhang, Lemeng, Wen, Xiaoping, Luo, Yongzhong, Yao, Dingquan, Cheng, Tianli, Cheng, Huanqing, Wang, Huina, Lou, Feng, Guo, Jing, Liang, Xiayuan, Cao, Shanbo, Chen, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781496/ https://www.ncbi.nlm.nih.gov/pubmed/31611986 http://dx.doi.org/10.3892/ol.2019.10791

Ejemplares similares

Comprehensive Molecular Profiling of Colorectal Cancer With Situs Inversus Totalis by Next-Generation Sequencing
por: Li, Hongsen, et al.
Publicado: (2022)

Comprehensive Molecular Characterization of Chinese Patients with Glioma by Extensive Next-Generation Sequencing Panel Analysis
por: Zeng, Chun, et al.
Publicado: (2021)

Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells
por: Zhang, Lemeng, et al.
Publicado: (2022)

Development and Validation of a Prognostic N6-Methyladenosine-Related Immune Gene Signature for Lung Adenocarcinoma
por: Zhang, Lemeng, et al.
Publicado: (2021)

Molecular Identification and Genetic Characterization of Early-Stage Multiple Primary Lung Cancer by Large-Panel Next-Generation Sequencing Analysis
por: Pei, Guotian, et al.
Publicado: (2021)

Multiple microarray analyses identify key genes associated with the development of Non-Small Cell Lung Cancer from Chronic Obstructive Pulmonary Disease
por: Zhang, Lemeng, et al.
Publicado: (2021)

Mutation patterns and evolutionary action score of TP53 enable identification of a patient population with poor prognosis in advanced non‐small cell lung cancer
por: Jiang, Wensheng, et al.
Publicado: (2022)

Efficacy and Safety of Afatinib in the Treatment of Advanced Non-Small-Cell Lung Cancer with EGFR Mutations: A Meta-Analysis of Real-World Evidence
por: Zhang, Lemeng, et al.
Publicado: (2021)

A Novel Risk Score Model of Lactate Metabolism for Predicting over Survival and Immune Signature in Lung Adenocarcinoma
por: Jiang, Zhou, et al.
Publicado: (2022)

Comparative genomic signatures in young and old Chinese patients with colorectal cancer
por: Wang, Fei, et al.
Publicado: (2021)

Neutrophil Extracellular Traps Facilitate A549 Cell Invasion and Migration in a Macrophage-Maintained Inflammatory Microenvironment
por: Zhang, Lemeng, et al.
Publicado: (2022)

The Evaluation of Prognostic Value and Immune Characteristics of Ferroptosis-Related Genes in Lung Squamous Cell Carcinoma
por: Su, Jialin, et al.
Publicado: (2023)

Identification of the key genes and characterizations of Tumor Immune Microenvironment in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC)
por: Zhang, Lemeng, et al.
Publicado: (2020)

Identification of Differentially Expressed Genes and miRNAs Associated with Esophageal Squamous Cell Carcinoma by Integrated Analysis of Microarray Data
por: Zhang, Lemeng, et al.
Publicado: (2020)

Discovery of targetable genetic alterations in advanced non-small cell lung cancer using a next-generation sequencing-based circulating tumor DNA assay
por: Hou, Helei, et al.
Publicado: (2017)

Molecular profiling and identification of prognostic factors in Chinese patients with small bowel adenocarcinoma
por: Pan, Hongming, et al.
Publicado: (2021)

Publisher Correction: Discovery of targetable genetic alterations in advanced non-small cell lung cancer using a next-generation sequencing-based circulating tumor DNA assay
por: Hou, Helei, et al.
Publicado: (2018)

Targeted Next-Generation Sequencing of Circulating Tumor DNA, Bone Marrow, and Peripheral Blood Mononuclear Cells in Pediatric AML
por: Ruan, Min, et al.
Publicado: (2021)

Clinical application of plasma mitochondrial DNA content in patients with lung cancer
por: Chen, Jianhua, et al.
Publicado: (2018)

Mutational pattern off homologous recombination repair (HRR)‐related genes in upper tract urothelial carcinoma
por: Yang, Kaiwei, et al.
Publicado: (2023)

A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors
por: Conroy, Jeffrey M., et al.
Publicado: (2021)

Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma
por: Ikeda, Sadakatsu, et al.
Publicado: (2018)

Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA
por: Poh, Jonathan, et al.
Publicado: (2022)

Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay
por: Saldivar, Juan-Sebastian, et al.
Publicado: (2023)

Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell Carcinoma
por: Kong, Wen, et al.
Publicado: (2021)

A novel approach for next‐generation sequencing of circulating tumor cells
por: Yee, Stephanie S., et al.
Publicado: (2016)

Molecular and clinical analysis of Chinese patients with anaplastic lymphoma kinase (ALK)‐rearranged non‐small cell lung cancer
por: Zhou, Xiaoyun, et al.
Publicado: (2019)

Identifying Circulating MicroRNA in Kawasaki Disease by Next-Generation Sequencing Approach
por: Weng, Ken-Pen, et al.
Publicado: (2021)

Comprehensive assessment of actionable genomic alterations in primary colorectal carcinoma using targeted next-generation sequencing
por: Jan, Yi-Hua, et al.
Publicado: (2022)

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples
por: Ng, Cedric Chuan-Young, et al.
Publicado: (2022)

Early application of metagenomics next-generation sequencing may significantly reduce unnecessary consumption of antibiotics in patients with fever of unknown origin
por: Chen, Hongmei, et al.
Publicado: (2023)

Circulating Cell-Free DNA-Based Comprehensive Molecular Analysis of Biliary Tract Cancers Using Next-Generation Sequencing
por: Csoma, Szilvia Lilla, et al.
Publicado: (2022)

Application of Comprehensive Genomic Profiling-Based Next-Generation Sequencing Assay to Improve Cancer Care in a Developing Country
por: Cifuentes, Claudia, et al.
Publicado: (2023)

Effectiveness of Treatment with Endostatin in Combination with Emcitabine, Carboplatin, and Gemcitabine in Patients with Advanced Non-small Cell Lung Cancer: A Retrospective Study
por: Yu, Xun, et al.
Publicado: (2018)

Eyelid squamous cell carcinoma in the setting of epidermodysplasia verruciformis (EV) diagnosed by next-generation sequencing: A case report and literature review
por: Wang, Linyan, et al.
Publicado: (2022)

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA
por: Chae, Young Kwang, et al.
Publicado: (2016)

Former smokers with non‐small‐cell lung cancers: a comprehensive investigation of clinicopathologic characteristics, oncogenic drivers, and prognosis
por: Zheng, Shanbo, et al.
Publicado: (2016)

TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome
por: Gray, Phillip N., et al.
Publicado: (2018)

Comprehensive genome profiling by next generation sequencing of circulating tumor DNA in solid tumors: a single academic institution experience
por: Caputo, Vincenza, et al.
Publicado: (2022)

Single-Center Experience with a Targeted Next Generation Sequencing Assay for Assessment of Relevant Somatic Alterations in Solid Tumors
por: Paasinen-Sohns, Aino, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_b06jpnk64hhvf10jpuie03pcts