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Pharmacokinetic Study of NADPH Oxidase Inhibitor Ewha-18278, a Pyrazole Derivative

In a previous study, the specific NOX1/2/4 inhibitor Ewha-18278 was confirmed as a possible treatment for osteoporosis both in vitro and in vivo. Here, we investigated the pharmacokinetics (PK) of the compound by intravenous (IV) and oral administrations to rats. Dimethyl sulfoxide (DMSO)-based and...

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Detalles Bibliográficos
Autores principales:	Lee, Seul Gee, Lee, Jaeok, Kim, Kyung Min, Lee, Kee-In, Bae, Yun Soo, Lee, Hwa Jeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781499/ https://www.ncbi.nlm.nih.gov/pubmed/31533299 http://dx.doi.org/10.3390/pharmaceutics11090482

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