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Development and Characterization of Eudragit(®)-Based Electrospun Nanofibrous Mats and Their Formulation into Nanofiber Tablets for the Modified Release of Furosemide

Furosemide, a chloride channel blocker ordinarily used as a high-ceiling or loop diuretic, is practically insoluble in water and dilute acids. Due to its acidic nature, furosemide is mostly absorbed in the stomach and in the upper small intestine. Efforts have focused on the development of sustained...

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Detalles Bibliográficos
Autores principales: Vlachou, Marilena, Kikionis, Stefanos, Siamidi, Angeliki, Kyriakou, Sotiria, Tsotinis, Andrew, Ioannou, Efstathia, Roussis, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781502/
https://www.ncbi.nlm.nih.gov/pubmed/31533252
http://dx.doi.org/10.3390/pharmaceutics11090480