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Electrospray-Based Microencapsulation of Epigallocatechin 3-Gallate for Local Delivery into the Intervertebral Disc

Locally delivered anti-inflammatory compounds can restore the homeostasis of the degenerated intervertebral disc (IVD). With beneficial effects on IVD cells, epigallocatechin 3-gallate (EGCG) is a promising therapeutic candidate. However, EGCG is prone to rapid degradation and/or depletion. Therefor...

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Detalles Bibliográficos
Autores principales: Loepfe, Moira, Duss, Anja, Zafeiropoulou, Katerina-Alexandra, Björgvinsdóttir, Oddny, D’Este, Matteo, Eglin, David, Fortunato, Giuseppino, Klasen, Juergen, Ferguson, Stephen J., Wuertz-Kozak, Karin, Krupkova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781552/
https://www.ncbi.nlm.nih.gov/pubmed/31480533
http://dx.doi.org/10.3390/pharmaceutics11090435