Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses

The sirtuins SIRT3 and SIRT5 are the main mitochondrial lysine deacetylase and desuccinylase, respectively. SIRT3 and SIRT5 regulate metabolism and redox homeostasis and have been involved in age-associated metabolic, neurologic and oncologic diseases. We have previously shown that single deficiency...

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Detalles Bibliográficos
Autores principales: Heinonen, Tytti, Ciarlo, Eleonora, Le Roy, Didier, Roger, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781768/
https://www.ncbi.nlm.nih.gov/pubmed/31632409
http://dx.doi.org/10.3389/fimmu.2019.02341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781768/
https://www.ncbi.nlm.nih.gov/pubmed/31632409
http://dx.doi.org/10.3389/fimmu.2019.02341

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