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In Planta Glycan Engineering and Functional Activities of IgE Antibodies
Human immunoglobulin E (IgE) is the most extensively glycosylated antibody isotype so glycans attached to the seven N-glycosites (NGS) in its Fab and Fc domains may modulate its functions. However, targeted modification of glycans in multiply glycosylated proteins remains a challenge. Here, we appli...
Autores principales: | Montero-Morales, Laura, Maresch, Daniel, Crescioli, Silvia, Castilho, Alexandra, Ilieva, Kristina M., Mele, Silvia, Karagiannis, Sophia N., Altmann, Friedrich, Steinkellner, Herta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781838/ https://www.ncbi.nlm.nih.gov/pubmed/31632959 http://dx.doi.org/10.3389/fbioe.2019.00242 |
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