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Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study

BACKGROUND: Adverse experiences, such as low care, overprotection, or abuse in childhood increase the likelihood of depression via their effects on personality traits. Similarly, being victimized in childhood may affect the likelihood of depression via personality traits. In this case-control study,...

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Autores principales: Tachi, Shuichiro, Asamizu, Miki, Uchida, Yoshihiro, Katayama, Shigemasa, Naruse, Mayu, Masuya, Jiro, Ichiki, Masahiko, Inoue, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781847/
https://www.ncbi.nlm.nih.gov/pubmed/31632031
http://dx.doi.org/10.2147/NDT.S220349
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author Tachi, Shuichiro
Asamizu, Miki
Uchida, Yoshihiro
Katayama, Shigemasa
Naruse, Mayu
Masuya, Jiro
Ichiki, Masahiko
Inoue, Takeshi
author_facet Tachi, Shuichiro
Asamizu, Miki
Uchida, Yoshihiro
Katayama, Shigemasa
Naruse, Mayu
Masuya, Jiro
Ichiki, Masahiko
Inoue, Takeshi
author_sort Tachi, Shuichiro
collection PubMed
description BACKGROUND: Adverse experiences, such as low care, overprotection, or abuse in childhood increase the likelihood of depression via their effects on personality traits. Similarly, being victimized in childhood may affect the likelihood of depression via personality traits. In this case-control study, we hypothesized that being victimized in childhood is associated with depression in adulthood via its effect on neuroticism, and verified this hypothesis using path analysis. SUBJECTS AND METHODS: Eighty-two major depressive disorder (MDD) patients and 350 age-and-sex matched healthy controls completed self-administered questionnaires of demographic data, Patient Health Questionnaire-9, neuroticism, and victimization. The association between victimization, neuroticism, and depressive symptoms or having major depression was investigated by path analysis. RESULTS: Multiple group path analysis, in which depressive symptoms were considered as dependent variables, showed that the direct effect of victimization in childhood on depressive symptoms was not statistically significant in either healthy controls or MDD patients (standardized path coefficient: 0.079 and 0.084, respectively), but their indirect effects via neuroticism were statistically significant (standardized path coefficient: 0.059 and 0.141, respectively). Path analysis, in which the distinction between healthy controls and MDD patients was a dependent variable, showed that both direct effects and indirect effects of victimization in childhood via neuroticism on the distinction between healthy controls and MDD patients were statistically significant (standardized path coefficient: 0.186 and 0.164, respectively). LIMITATIONS: Recall bias and the relatively small number of MDD patients are limitations of this study. Because it was a case-control survey, this study could not make any conclusions regarding causal associations. CONCLUSION: This study suggests the possibility of causal associations between victimization in childhood and depressive symptoms or MDD in adulthood, and the mediation of this association by neuroticism.
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spelling pubmed-67818472019-10-18 Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study Tachi, Shuichiro Asamizu, Miki Uchida, Yoshihiro Katayama, Shigemasa Naruse, Mayu Masuya, Jiro Ichiki, Masahiko Inoue, Takeshi Neuropsychiatr Dis Treat Original Research BACKGROUND: Adverse experiences, such as low care, overprotection, or abuse in childhood increase the likelihood of depression via their effects on personality traits. Similarly, being victimized in childhood may affect the likelihood of depression via personality traits. In this case-control study, we hypothesized that being victimized in childhood is associated with depression in adulthood via its effect on neuroticism, and verified this hypothesis using path analysis. SUBJECTS AND METHODS: Eighty-two major depressive disorder (MDD) patients and 350 age-and-sex matched healthy controls completed self-administered questionnaires of demographic data, Patient Health Questionnaire-9, neuroticism, and victimization. The association between victimization, neuroticism, and depressive symptoms or having major depression was investigated by path analysis. RESULTS: Multiple group path analysis, in which depressive symptoms were considered as dependent variables, showed that the direct effect of victimization in childhood on depressive symptoms was not statistically significant in either healthy controls or MDD patients (standardized path coefficient: 0.079 and 0.084, respectively), but their indirect effects via neuroticism were statistically significant (standardized path coefficient: 0.059 and 0.141, respectively). Path analysis, in which the distinction between healthy controls and MDD patients was a dependent variable, showed that both direct effects and indirect effects of victimization in childhood via neuroticism on the distinction between healthy controls and MDD patients were statistically significant (standardized path coefficient: 0.186 and 0.164, respectively). LIMITATIONS: Recall bias and the relatively small number of MDD patients are limitations of this study. Because it was a case-control survey, this study could not make any conclusions regarding causal associations. CONCLUSION: This study suggests the possibility of causal associations between victimization in childhood and depressive symptoms or MDD in adulthood, and the mediation of this association by neuroticism. Dove 2019-10-03 /pmc/articles/PMC6781847/ /pubmed/31632031 http://dx.doi.org/10.2147/NDT.S220349 Text en © 2019 Tachi et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Tachi, Shuichiro
Asamizu, Miki
Uchida, Yoshihiro
Katayama, Shigemasa
Naruse, Mayu
Masuya, Jiro
Ichiki, Masahiko
Inoue, Takeshi
Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study
title Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study
title_full Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study
title_fullStr Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study
title_full_unstemmed Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study
title_short Victimization In Childhood Affects Depression In Adulthood Via Neuroticism:A Path Analysis Study
title_sort victimization in childhood affects depression in adulthood via neuroticism:a path analysis study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781847/
https://www.ncbi.nlm.nih.gov/pubmed/31632031
http://dx.doi.org/10.2147/NDT.S220349
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