KLB gene polymorphism is associated with obesity and non-alcoholic fatty liver disease in the Han Chinese

Klotho beta (KLB) mediates binding of fibroblast growth factor (FGF) 21 to the FGF receptor (FGFR). FGF21-KLB-FGFR signaling regulates multiple metabolic systems in the liver, and we hypothesized that FGF21, KLB and FGFR single-nucleotide polymorphisms (SNPs) are involved in hepatic lipid accumulati...

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Detalles Bibliográficos
Autores principales: Ji, Fang, Liu, Ye, Hao, Jun-Gui, Wang, Li-Ping, Dai, Ming-Jia, Shen, Gui-Fang, Yan, Xue-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781984/
https://www.ncbi.nlm.nih.gov/pubmed/31548436
http://dx.doi.org/10.18632/aging.102293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781984/
https://www.ncbi.nlm.nih.gov/pubmed/31548436
http://dx.doi.org/10.18632/aging.102293

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