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KLB gene polymorphism is associated with obesity and non-alcoholic fatty liver disease in the Han Chinese
Klotho beta (KLB) mediates binding of fibroblast growth factor (FGF) 21 to the FGF receptor (FGFR). FGF21-KLB-FGFR signaling regulates multiple metabolic systems in the liver, and we hypothesized that FGF21, KLB and FGFR single-nucleotide polymorphisms (SNPs) are involved in hepatic lipid accumulati...
Autores principales: | Ji, Fang, Liu, Ye, Hao, Jun-Gui, Wang, Li-Ping, Dai, Ming-Jia, Shen, Gui-Fang, Yan, Xue-Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781984/ https://www.ncbi.nlm.nih.gov/pubmed/31548436 http://dx.doi.org/10.18632/aging.102293 |
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