miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells

Clinically, one of the principal factors in the failure of advanced colorectal cancer (CRC) treatment is chemoresistance to 5-fluorouracil (5FU)-based chemotherapy. Although microRNA-375-3p (miR-375) is considered a tumor suppressor in multiple cancers, the mechanism of miR-375 in the regulation of...

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Detalles Bibliográficos
Autores principales: Xu, Xueni, Chen, Xiaoxiang, Xu, Mu, Liu, Xiangxiang, Pan, Bei, Qin, Jian, Xu, Tao, Zeng, Kaixuan, Pan, Yuqin, He, Bangshun, Sun, Huiling, Sun, Li, Wang, Shukui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781994/
https://www.ncbi.nlm.nih.gov/pubmed/31543507
http://dx.doi.org/10.18632/aging.102214

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